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KMID : 0359920110300050498
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Korean Journal of Nephrology
2011 Volume.30 No. 5 p.498 ~ p.505
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Prevalence of Primary Glomerulonephritis - A Single Center Analysis
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Kim Ki-Hyun
Son Young-Ki
Lee Su-Mi
An Won-Suk
Kim Seong-Eun
Rha Seo-Hee
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Abstract
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Purpose:To evaluate the exact prevalence of primary glomerular diseases in Korea.
Methods:We analyzed a retrospective cohort of biopsy proven 1,100 patients with primary glomerular disease in OO Hospital from April 1990 to March 2010.
Results:Pathologic diagnosises of 1,100 cases were as follows: IgA nephropathy (IgAN) , 557 cases (50.6%), was the most common followed by 200 cases (18.1%) of minor glomerular abnormalities (MGA), 168 cases (15.2%) of focal segmental glomerulosclerosis (FSGS), 93 cases (8.0%) of membranous nephropathy (MN), 31 cases (2.8%) of membranoproliferative glomerulonephritis type I (MPGN), 17 cases (1.5%) of focal glomerulonephritis and 7 cases (0.6%) of diffuse mesangial proliferative glomerulonephritis (DMGN) in order. In idiopathic nephrotic syndrome, the most common pathologic diagnosis was minimal change nephrotic syndrome (MCNS) (40.2%), followed by FSGS (27.5%), MN (24.2%), MPGN (8.1%) and DMGN (0.5%). When the incidence rates between 1990-1992 and 2008-2010 were compared, IgAN and FSGS increased from 34.7, 12.5 to 47.8%, 30.4%, but MCNS (from 33.3 to 6.5 %) decreased significantly
Conclusion:IgAN was the most common primary glomerulonephritis. During the past 20 years, the prevalence of IgAN and FSGS were increased, while MCNS and MN were decreased.
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KEYWORD
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Biopsy, Glomerulonephritis, Prevalenc
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